Protein Name:
Thioredoxin-dependent peroxide reductase, mitochondrial
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UniprotKB/SwissProt ID: P35705 (P35705)
Gene Name:
PRDX3
Organism: Bos taurus (Bovine)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (By similarity). Required for the maintenance of physical strength (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix. Cytoplasm. Early endosome
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Graphical Visualization of S-nitrosylation Sites:
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