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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Alpha-actinin-2

UniprotKB/SwissProt ID: P35609 (P35609)

Gene Name: ACTN2

Organism: Homo sapiens (Human)

Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, myofibril, sarcomere, Z line

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001589 Actinin_actin-bd_CS
IPR001715 CH_dom
IPR036872 CH_dom_sf
IPR011992 EF-hand-dom_pair
IPR014837 EF-hand_Ca_insen
IPR002048 EF_hand_dom
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat

The S-nitrosylation sites of P35609

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 161 TSAKEGLLLW C QRKTAPYRNV   
2 339 KHKPPKVQEK C QLEINFNTLQ    37478858
3 48 KQQRKTFTAW C NSHLRKAGTQ