Protein Name:
Myosin-10
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UniprotKB/SwissProt ID: P35580 (P35580)
Gene Name:
MYH10
Organism: Homo sapiens (Human)
Function: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9 (Microbial infection) Acts as a receptor for herpes simplex virus 1/HHV-1 envelope glycoprotein B
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell projection, lamellipodium. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P35580
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1011 |
KKLMEDRIAE C SSQLAEEEEK |
CCCCCCCCCH H HEEEEEEEEE |
3.33% |
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| 2 |
1238 |
GLETDNKELA C EVKVLQQVKA |
CCCCCCCCCH H HEEEEEEEEE |
10.91% |
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| 3 |
176 |
LQDREDQSIL C TGESGAGKTE |
CCCCCCCCCH H HEEEEEEEEE |
4.35% |
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| 4 |
576 |
PRQLKDKADF C IIHYAGKVDY |
CCCCCCCCCH H HEEEEEEEEE |
2.69% |
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| 5 |
678 |
LRNTNPNFVR C IIPNHEKRAG |
CCCCCCCCCH H HEEEEEEEEE |
2.51% |
37478858
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| 6 |
701 |
DPHLVLDQLR C NGVLEGIRIC |
CCCCCCCCCH H HEEEEEEEEE |
7.65% |
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| 7 |
823 |
LSALKVLQRN C AAYLKLRHWQ |
CCCCCCCCCH H HEEEEEEEEE |
2.2% |
2212679
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| 8 |
95 |
SKVEDMAELT C LNEASVLHNL |
CCCCCCCCCH H HEEEEEEEEE |
6.33% |
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