Protein Name:
Inward rectifier potassium channel 2
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UniprotKB/SwissProt ID: P35561 (P35561)
Gene Name:
Kcnj2
Organism: Mus musculus (Mouse)
Function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium (PubMed:7680768, PubMed:8282096). Can be blocked by extracellular barium and cesium. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell membrane, sarcolemma, T-tubule
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P35561
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
76 |
QRYLADIFTT C VDIRWRWMLV |
CCCCCCCCEE E EECCCHHHHH |
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