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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

UniprotKB/SwissProt ID: P35487 (P35487)

Gene Name: Pdha2

Organism: Mus musculus (Mouse)

Function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001017 DH_E1
IPR050642 PDH_E1_Alpha_Subunit
IPR017597 Pyrv_DH_E1_asu_subgrp-y
IPR029061 THDP-binding

The S-nitrosylation sites of P35487

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 101 FCHLCDGQEA C CVGLEAGINP  CHHHHHHHHH H HHHHHCCCHH  1.58%
2 102 CHLCDGQEAC C VGLEAGINPT  CHHHHHHHHH H HHHHHCCCHH  3.33%
3 262 GLRVNGMDIL C VREATKFAAD  CHHHHHHHHH H HHHHHCCCHH  2.5% 21278135