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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ras-related protein Rab-22A

UniprotKB/SwissProt ID: P35285 (P35285)

Gene Name: Rab22a

Organism: Mus musculus (Mouse)

Function: Plays a role in endocytosis and intracellular protein transport (PubMed:19759177, PubMed:27718357). Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endosome membrane. Cell membrane. Early endosome. Late endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase

The S-nitrosylation sites of P35285

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 9 --MALRELKV C LLGDTGVGKS  CCCCCCEEEE E CCCCCCCHHH  2.19% 20925432