Protein Name:
Replication factor C subunit 1
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UniprotKB/SwissProt ID: P35251 (P35251)
Gene Name:
RFC1
Organism: Homo sapiens (Human)
Function: Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA (PubMed:9488738). This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Can bind single- or double-stranded DNA
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P35251
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
607 |
TIIGQQGDQS C ANKLLRWLRN |
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| 2 |
767 |
HPKIRSLVHY C FDLRFQRPRV |
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| 3 |
916 |
MLLSRAADSI C DGDLVDSQIR |
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