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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine hydroxymethyltransferase, cytosolic

UniprotKB/SwissProt ID: P34896 (P34896)

Gene Name: SHMT1

Organism: Homo sapiens (Human)

Function: Interconversion of serine and glycine (PubMed:24698160, PubMed:8505317)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
IPR015422 PyrdxlP-dep_Trfase_small
IPR001085 Ser_HO-MeTrfase
IPR049943 Ser_HO-MeTrfase-like
IPR019798 Ser_HO-MeTrfase_PLP_BS
IPR039429 SHMT-like_dom

The S-nitrosylation sites of P34896

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 110 ALQAYKLDPQ C WGVNVQPYSG   
2 204 HPKLIIAGTS C YSRNLEYARL   
3 335 KVYQHQVVAN C RALSEALTEL   
4 389 ACSIACNKNT C PGDRSALRPS   
5 96 TEFIDELETL C QKRALQAYKL