Protein Name:
ER lumen protein-retaining receptor 2
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UniprotKB/SwissProt ID: P33947 (P33947)
Gene Name:
KDELR2
Organism: Homo sapiens (Human)
Function: Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (PubMed:1325562, PubMed:18086916, PubMed:33053334). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasmic vesicle, COPI-coated vesicle membrane
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR000133
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ER_ret_rcpt |
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The S-nitrosylation sites of P33947
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
29 |
LLLKIWKTRS C AGISGKSQLL |
CCCHHCCCCH H HHHHHHHHHH |
3.47% |
2212679
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