Protein Name:
Cytochrome P450 2F2
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UniprotKB/SwissProt ID: P33267 (P33267)
Gene Name:
Cyp2f2
Organism: Mus musculus (Mouse)
Function: Involved in the regio- and stereoselective transformation of naphthalene to trans-1R-hydroxy-2R-glutathionyl-1,2-dihydronaphthalene in the presence of glutathione and glutathione S-transferases. It specifically catalyzes the production of a very reactive and potentially toxic intermediate, the 2R,2S arene oxide, that is associated with necrosis of the unciliated bronchiolar epithelial cells or club cells in lung
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Microsome membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P33267
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
267 |
DPNSPRDFID C FLTKMAQEKQ |
CCHHHHHHHH H HHHHHHHHHH |
2.29% |
22178444
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| 2 |
436 |
FMPFSAGRRL C LGEPLARMEL |
CCHHHHHHHH H HHHHHHHHHH |
4.32% |
22178444
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| 3 |
487 |
LGNLPRPFQL C MHIR------ |
CCHHHHHHHH H HHHHHHHHHH |
0.98% |
22178444
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