UniprotKB/SwissProt ID: P32970 (P32970)
Gene Name:
CD70
Organism: Homo sapiens (Human)
Function: Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells (PubMed:28011863, PubMed:28011864, PubMed:8387892). The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells (PubMed:28011863, PubMed:28011864)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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