UniprotKB/SwissProt ID: P32507 (P32507)
Gene Name:
Nectin2
Organism: Mus musculus (Mouse)
Function: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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