UniprotKB/SwissProt ID: P32239 (P32239)
Gene Name:
CCKBR
Organism: Homo sapiens (Human)
Function: Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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