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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Macrosialin

UniprotKB/SwissProt ID: P31996 (P31996)

Gene Name: Cd68

Organism: Mus musculus (Mouse)

Function: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endosome membrane. Lysosome membrane. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR048528 Lamp2-like_luminal
IPR018134 LAMP_CS
IPR002000 Lysosome-assoc_membr_glycop