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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sodium- and chloride-dependent betaine transporter

UniprotKB/SwissProt ID: P31651 (P31651)

Gene Name: Slc6a12

Organism: Mus musculus (Mouse)

Function: Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (By similarity). May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (Probable). Probably also involved in renal and hepatic osmotic regulation (PubMed:22071246)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Basolateral cell membrane. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000175 Na/ntran_symport
IPR002983 Na/ntran_symport_betaine
IPR037272 SNS_sf