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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dipeptidase 1

UniprotKB/SwissProt ID: P31428 (P31428)

Gene Name: Dpep1

Organism: Mus musculus (Mouse)

Function: Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 (PubMed:12738806, PubMed:31442408, PubMed:9560193). Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (PubMed:12738806, PubMed:9560193). Also possesses beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics (PubMed:12738806) Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane. Cell projection, microvillus membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000180 Dipep_AS
IPR032466 Metal_Hydrolase
IPR008257 Pept_M19

The S-nitrosylation sites of P31428

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 242 IFSHSSAYSL C PHRRNVPDDV