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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glycylpeptide N-tetradecanoyltransferase 1

UniprotKB/SwissProt ID: P30419 (P30419)

Gene Name: NMT1

Organism: Homo sapiens (Human)

Function: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (PubMed:22865860, PubMed:25255805, PubMed:32686708, PubMed:34999170, PubMed:9353336, PubMed:9506952). Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3' (PubMed:32103017, PubMed:32111831). Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle (PubMed:32103017)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytosol. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016181 Acyl_CoA_acyltransferase
IPR000903 NMT
IPR022677 NMT_C
IPR022678 NMT_CS
IPR022676 NMT_N

The S-nitrosylation sites of P30419

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 249 EKKMVEINFL C VHKKLRSKRV