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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Leucine aminopeptidase 1

UniprotKB/SwissProt ID: P30184 (P30184)

Gene Name: LAP1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (Probable). Possesses leucine aminopeptidase activity against the model substrate leucine-amido methyl coumarin (PubMed:22493451). Possesses Cys-Gly dipeptidase activity. In addition, can cleave Cys-Leu and Leu-Cys dipeptides (PubMed:25716890) Functions as a molecular chaperone to protect proteins from heat-induced damage

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011356 Leucine_aapep/pepB
IPR043472 Macro_dom-like
IPR000819 Peptidase_M17_C
IPR023042 Peptidase_M17_leu_NH2_pept
IPR008283 Peptidase_M17_N

The S-nitrosylation sites of P30184

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 305 GGYNIKTGPG C SIELMKFDMG   
2 388 LTLADALVYA C NQGVDKIVDL