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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

UniprotKB/SwissProt ID: P30154 (P30154)

Gene Name: PPP2R1B

Organism: Homo sapiens (Human)

Function: The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000357 HEAT
IPR021133 HEAT_type_2
IPR054573 PP2A/SF3B1-like_HEAT
IPR051023 PP2A_Regulatory_Subunit_A

The S-nitrosylation sites of P30154

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 160 GDWFTSRTSA C GLFSVCYPRA  CCCCCCCCCC C CCCCCCCCCC  4.95%
2 166 RTSACGLFSV C YPRASNAVKA  CCCCCCCCCC C CCCCCCCCCC  3.61%
3 306 IPAFQNLLKD C EAEVRAAAAH  CCCCCCCCCC C CCCCCCCCCC  5.22%
4 402 VRLNIISNLD C VNEVIGIRQL  CCCCCCCCCC C CCCCCCCCCC  3.89% 22178444