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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transketolase

UniprotKB/SwissProt ID: P29401 (P29401)

Gene Name: TKT

Organism: Homo sapiens (Human)

Function: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR051424 Transketolase-like
IPR005475 Transketolase-like_Pyr-bd
IPR020826 Transketolase_BS
IPR033248 Transketolase_C
IPR049557 Transketolase_CS
IPR005474 Transketolase_N

The S-nitrosylation sites of P29401

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 133 GSLGQGLGAA C GMAYTGKYFD  CCCCCCCCHH H HHHHHHHHHH  3.67%
2 206 QHQMDIYQKR C EAFGWHAIIV  CCCCCCCCHH H HHHHHHHHHH  5.95%
3 225 IVDGHSVEEL C KAFGQAKHQP  CCCCCCCCHH H HHHHHHHHHH  3.19%
4 362 KKEHPDRFIE C YIAEQNMVSI  CCCCCCCCHH H HHHHHHHHHH  2.26%
5 386 CATRNRTVPF C STFAAFFTRA  CCCCCCCCHH H HHHHHHHHHH  2.83% 25040305
37478858
6 468 VELAANTKGI C FIRTSRPENA  CCCCCCCCHH H HHHHHHHHHH  2.94%