UniprotKB/SwissProt ID: P29391 (P29391)
Gene Name:
Ftl1
Organism: Mus musculus (Mouse)
Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Degraded to release iron upon autophagy activation by nutrient starvation (PubMed:25327288)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasmic vesicle, autophagosome. Autolysosome
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