Protein Name:
Ribonuclease inhibitor
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UniprotKB/SwissProt ID: P29315 (P29315)
Gene Name:
Rnh1
Organism: Rattus norvegicus (Rat)
Function: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG) (PubMed:1536887). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress (By similarity). Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P29315
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
243 |
KLGNTGIAAL C SGLLLPSCRL |
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| 2 |
261 |
CRLRTLWLWD C DVTAEGCKDL |
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| 3 |
268 |
LWDCDVTAEG C KDLCRVLRAK |
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| 4 |
80 |
LVLQGLQNPT C KIQKLSLQNC |
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| 5 |
90 |
CKIQKLSLQN C SLTEAGCGVL |
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