Protein Name:
Tripeptidyl-peptidase 2
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UniprotKB/SwissProt ID: P29144 (P29144)
Gene Name:
TPP2
Organism: Homo sapiens (Human)
Function: Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway (PubMed:25525876, PubMed:30533531). It plays an important role in intracellular amino acid homeostasis (PubMed:25525876). Stimulates adipogenesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P29144
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1125 |
KQKSTLVDAL C RKGCALADHL |
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| 2 |
150 |
PVHRVALAEA C RKQEEFDVAN |
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| 3 |
28 |
KKETGAASFL C RYPEYDGRGV |
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| 4 |
342 |
ATHWPNSGRI C EVINEAVWKH |
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| 5 |
733 |
PVLGGKAIEF C IARWWASLSD |
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| 6 |
787 |
SSLKYEDLAP C ITLKNWVQTL |
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