Protein Name:
Murinoglobulin-1
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UniprotKB/SwissProt ID: P28665 (P28665)
Gene Name:
Mug1
Organism: Mus musculus (Mouse)
Function: A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P28665
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1469 |
EMAFAEYSSP C STDKQNV--- |
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| 2 |
251 |
VNDEVLSVTA C GKYTYGKPVP |
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| 3 |
587 |
LQVTASPQSL C GLRAVDQSVL |
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