Protein Name:
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
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UniprotKB/SwissProt ID: P28331 (P28331)
Gene Name:
NDUFS1
Organism: Homo sapiens (Human)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P28331
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
367 |
LLNRVDSDTL C TEEVFPTAGA |
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| 2 |
554 |
VLFLLGADGG C ITRQDLPKDC |
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| 3 |
710 |
ISRASQTMAK C VKAVTEGAQA |
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| 4 |
727 |
GAQAVEEPSI C ---------- |
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