Protein Name:
Deoxycytidine kinase
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UniprotKB/SwissProt ID: P27707 (P27707)
Gene Name:
DCK
Organism: Homo sapiens (Human)
Function: Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine (PubMed:12808445, PubMed:18377927, PubMed:19159229, PubMed:1996353, PubMed:20614893, PubMed:20637175). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents (PubMed:12808445)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P27707
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
45 |
STFVNILKQL C EDWEVVPEPV |
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| 2 |
59 |
EVVPEPVARW C NVQSTQDEFE |
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| 3 |
9 |
--MATPPKRS C PSFSASSEGT |
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