\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: 14-3-3 protein theta

UniprotKB/SwissProt ID: P27348 (P27348)

Gene Name: YWHAQ

Organism: Homo sapiens (Human)

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
IPR042584 14-3-3_theta

The S-nitrosylation sites of P27348

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 134 DYFRYLAEVA C GDDRKQTIDN  CCHHHHHHHH H HHHHHHHHHH  8.09% 20140087
19483679
19101475
2 189 YEILNNPELA C TLAKTAFDEA  CCHHHHHHHH H HHHHHHHHHH  5.11%
3 237 LWTSDSAGEE C DAAEGAEN--  CCHHHHHHHH H HHHHHHHHHH  3.62%
4 25 QAERYDDMAT C MKAVTEQGAE  CCHHHHHHHH H HHHHHHHHHH  1.59% 2212679
16648260
5 94 EKVESELRSI C TTVLELLDKY  CCHHHHHHHH H HHHHHHHHHH  2.48% 19483679
25040305