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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serum paraoxonase/arylesterase 1

UniprotKB/SwissProt ID: P27169 (P27169)

Gene Name: PON1

Organism: Homo sapiens (Human)

Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011042 6-blade_b-propeller_TolB-like
IPR002640 Arylesterase
IPR008363 Paraoxonase1
IPR051288 Serum_paraoxonase/arylesterase