UniprotKB/SwissProt ID: P27038 (P27038)
Gene Name:
Acvr2a
Organism: Mus musculus (Mouse)
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (PubMed:23527555)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
|
|
|
