Protein Name:
Catenin alpha-2
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UniprotKB/SwissProt ID: P26232 (P26232)
Gene Name:
CTNNA2
Organism: Homo sapiens (Human)
Function: May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system (By similarity). Required for proper regulation of cortical neuronal migration and neurite growth (PubMed:30013181). It acts as a negative regulator of Arp2/3 complex activity and Arp2/3-mediated actin polymerization (PubMed:30013181). It thereby suppresses excessive actin branching which would impair neurite growth and stability (PubMed:30013181). Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell projection, axon. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P26232
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
322 |
SGAALMADSS C TRDDRRERIV |
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