UniprotKB/SwissProt ID: P25095 (P25095)
Gene Name:
Agtr1
Organism: Rattus norvegicus (Rat)
Function: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney (PubMed:10747880, PubMed:2041570). The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C (PubMed:10747880)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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