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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Histamine H2 receptor

UniprotKB/SwissProt ID: P25021 (P25021)

Gene Name: HRH2

Organism: Homo sapiens (Human)

Function: The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000503 Histamine_H2_rcpt