Protein Name:
Insulin-like growth factor-binding protein 6
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UniprotKB/SwissProt ID: P24592 (P24592)
Gene Name:
IGFBP6
Organism: Homo sapiens (Human)
Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed:24003225)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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Graphical Visualization of S-nitrosylation Sites:
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