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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Elongation factor 1-beta

UniprotKB/SwissProt ID: P24534 (P24534)

Gene Name: EEF1B2

Organism: Homo sapiens (Human)

Function: Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1) (By similarity). Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036219 eEF-1beta-like_sf
IPR018940 EF-1_beta_acid_region_euk
IPR049720 EF1B_bsu/dsu
IPR014038 EF1B_bsu/dsu_GNE
IPR036282 Glutathione-S-Trfase_C_sf
IPR014717 Transl_elong_EF1B/ribsomal_bS6
IPR001326 Transl_elong_EF1B_B/D_CS

The S-nitrosylation sites of P24534

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 50 AVSSPPPADL C HALRWYNHIK