Protein Name:
Thimet oligopeptidase
|
UniprotKB/SwissProt ID: P24155 (P24155)
Gene Name:
Thop1
Organism: Rattus norvegicus (Rat)
Function: Involved in the metabolism of neuropeptides under 20 amino acid residues long (PubMed:2261476). Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments (By similarity). Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (PubMed:12500972, PubMed:18077343)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P24155
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
682 |
LLSKGLQVEG C EPPAC----- |
|
|
|
|
