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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: S-adenosylmethionine synthase 1

UniprotKB/SwissProt ID: P23686 (P23686)

Gene Name: SAM1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022631 ADOMET_SYNTHASE_CS
IPR022630 S-AdoMet_synt_C
IPR022629 S-AdoMet_synt_central
IPR022628 S-AdoMet_synt_N
IPR002133 S-AdoMet_synthetase
IPR022636 S-AdoMet_synthetase_sfam

The S-nitrosylation sites of P23686

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 114 AQGVHGHFTK C PEEIGAGDQG  CCEEEEECCC C CCCCCCHHHH  4.69% 16365035
2 42 LEQDPDSKVA C ETCTKTNMVM  CCEEEEECCC C CCCCCCHHHH  5.08%
3 45 DPDSKVACET C TKTNMVMVFG  CCEEEEECCC C CCCCCCHHHH  1.39%
4 90 SDDVGLDADK C KVLVNIEQQS  CCEEEEECCC C CCCCCCHHHH  3.66%