Protein Name:
40-kDa huntingtin-associated protein
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UniprotKB/SwissProt ID: P23610 (P23610)
Gene Name:
F8A1
Organism: Homo sapiens (Human)
Function: RAB5A effector molecule that is involved in vesicular trafficking of early endosomes (PubMed:16476778). Mediates the recruitment of HTT by RAB5A onto early endosomes. The HTT-F8A1/F8A2/F8A3-RAB5A complex stimulates early endosomal interaction with actin filaments and inhibits interaction with microtubules, leading to the reduction of endosome motility (PubMed:16476778)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Early endosome. Nucleus, nuclear body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P23610
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
110 |
QERDARQRLV C PAAYGEPLQA |
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19483679
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