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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Band 3 anion transport protein

UniprotKB/SwissProt ID: P23562 (P23562)

Gene Name: Slc4a1

Organism: Rattus norvegicus (Rat)

Function: Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Basolateral cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001717 Anion_exchange
IPR002977 Anion_exchange_1
IPR018241 Anion_exchange_CS
IPR013769 Band3_cytoplasmic_dom
IPR011531 HCO3_transpt-like_TM_dom
IPR003020 HCO3_transpt_euk
IPR016152 PTrfase/Anion_transptr