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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Receptor-type tyrosine-protein phosphatase zeta

UniprotKB/SwissProt ID: P23471 (P23471)

Gene Name: PTPRZ1

Organism: Homo sapiens (Human)

Function: Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Secreted. Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR041887 Alpha_CARP_receptor-type
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR029021 Prot-tyrosine_phosphatase-like
IPR050348 Protein-Tyr_Phosphatase
IPR000242 PTP_cat
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 Tyr_Pase_dom