Protein Name:
Anion exchange protein 2
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UniprotKB/SwissProt ID: P23347 (P23347)
Gene Name:
Slc4a2
Organism: Rattus norvegicus (Rat)
Function: Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:2371270). Plays an important role in osteoclast differentiation and function (By similarity). Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity). Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Apical cell membrane. Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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