Protein Name:
Catechol O-methyltransferase
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UniprotKB/SwissProt ID: P21964 (P21964)
Gene Name:
COMT
Organism: Homo sapiens (Human)
Function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P21964
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
145 |
RLITIEINPD C AAITQRMVDF |
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| 2 |
207 |
YLPDTLLLEE C GLLRKGTVLL |
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| 3 |
223 |
GTVLLADNVI C PGAPDFLAHV |
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| 4 |
83 |
QSVLEAIDTY C EQKEWAMNVG |
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