Protein Name:
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
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UniprotKB/SwissProt ID: P21912 (P21912)
Gene Name:
SDHB
Organism: Homo sapiens (Human)
Function: Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:26925370, PubMed:27604842). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P21912
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
249 |
SLYRCHTIMN C TRTCPKGLNP |
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| 2 |
68 |
MQTYEVDLNK C GPMVLDALIK |
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