Protein Name:
Inosine-5'-monophosphate dehydrogenase 1
|
UniprotKB/SwissProt ID: P20839 (P20839)
Gene Name:
IMPDH1
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of P20839
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
215 |
KKGKLPIVND C DELVAIIART |
|
|
|
| 2 |
246 |
ASKDSQKQLL C GAAVGTREDD |
|
|
|
|
