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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Calpastatin

UniprotKB/SwissProt ID: P20810 (P20810)

Gene Name: CAST

Organism: Homo sapiens (Human)

Function: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR026998 Calpastatin
IPR001259 Prot_inh_calpain

The S-nitrosylation sites of P20810

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 241 AIDALSSDFT C GSPTAAGKKT  CCCCCCCCCC H HHHCCCCCCC  5.26%
2 328 AKAKEEKLEK C GEDDETIPSE  CCCCCCCCCC H HHHCCCCCCC  5.43%
3 381 ELSEDFDRSE C KEKPSKPTEK  CCCCCCCCCC H HHHCCCCCCC  7.91%
4 408 AAPAPVSEAV C RTSMCSIQSA  CCCCCCCCCC H HHHCCCCCCC  5.18% 22178444
20140087
5 413 VSEAVCRTSM C SIQSAPPEPA  CCCCCCCCCC H HHHCCCCCCC  3.04% 2212679
6 661 IDALSGDLDS C PSTTETSQNT  CCCCCCCCCC H HHHCCCCCCC  2.85% 22178444
20140087