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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cation-dependent mannose-6-phosphate receptor

UniprotKB/SwissProt ID: P20645 (P20645)

Gene Name: M6PR

Organism: Homo sapiens (Human)

Function: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lysosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028927 Man-6-P_rcpt
IPR000296 Man-6-P_rcpt_cation_dep
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR044865 MRH_dom

The S-nitrosylation sites of P20645

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 145 EQRRAVVMIS C NRHTLADNFN   
2 32 RESWQTEEKT C DLVGEKGKES