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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Interferon-induced GTP-binding protein Mx2

UniprotKB/SwissProt ID: P20592 (P20592)

Gene Name: MX2

Organism: Homo sapiens (Human)

Function: Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Nucleus, nuclear pore complex

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022812 Dynamin
IPR001401 Dynamin_GTPase
IPR019762 Dynamin_GTPase_CS
IPR045063 Dynamin_N
IPR000375 Dynamin_stalk
IPR030381 G_DYNAMIN_dom
IPR003130 GED
IPR020850 GED_dom
IPR027417 P-loop_NTPase