Protein Name:
Thioredoxin-dependent peroxide reductase, mitochondrial
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UniprotKB/SwissProt ID: P20108 (P20108)
Gene Name:
Prdx3
Organism: Mus musculus (Mouse)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (By similarity). Required for the maintenance of physical strength (PubMed:27037278)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Cytoplasm. Early endosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of P20108
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
230 |
FQFVETHGEV C PANWTPESPT |
CCHHHHHHHH H HHHHHHHHHH |
1.99% |
24895380
22588120
21278135
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