UniprotKB/SwissProt ID: P19357 (P19357)
Gene Name:
Slc2a4
Organism: Rattus norvegicus (Rat)
Function: Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation (PubMed:2211693, PubMed:2645527, PubMed:2649253). Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells (PubMed:2211693, PubMed:2645527, PubMed:2649253). Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell (PubMed:2211693, PubMed:2645527, PubMed:2649253)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endomembrane system. Cytoplasm, perinuclear region
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