UniprotKB/SwissProt ID: P19107 (P19107)
Gene Name:
Arr2
Organism: Drosophila melanogaster (Fruit fly)
Function: Regulates photoreceptor cell deactivation (PubMed:36994075, PubMed:8316831). Arr1 and Arr2 proteins are mediators of rhodopsin inactivation and are essential for the termination of the phototransduction cascade (PubMed:8316831). Involved in regulating normal cycles of per nuclear accumulation in brain circadian neurons and thus is important for normal circadian behavior (PubMed:36994075). In the dark, functions with Arr1 to promote the formation of cytosolic Bdbt foci, which are required for dco localization to photoreceptor nuclei where it phosphorylates and activates degradation of per (PubMed:36994075)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell projection, rhabdomere
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