UniprotKB/SwissProt ID: P18581 (P18581)
Gene Name:
Slc7a2
Organism: Mus musculus (Mouse)
Function: Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:8195186, PubMed:8385111, PubMed:9174363). May play a role in classical or alternative activation of macrophages via its role in arginine transport (PubMed:16670299) Functions as a low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine) Functions as a permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine than isoform 1
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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